Post-Operative Nausea and Vomiting Market Report 2025: Surge in Surgical Procedures Fuels $2.97 Billion Growth in PONV Market by 2029

Post-operative nausea and vomiting (PONV) market to rise from $2.11B in 2024 to $2.97B in 2029, driven by innovations in antiemetic therapies, personalized medicine, and digital health technologies. Key players include Pfizer, Merck, and Novartis. North America leads, but Asia-Pacific grows fastest.


Dublin, July 25, 2025 (GLOBE NEWSWIRE) -- The "Post-Operative Nausea and Vomiting Market Report 2025" report has been added to ResearchAndMarkets.com's offering.

The post-operative nausea and vomiting market size has grown strongly in recent years. It will grow from $2.11 billion in 2024 to $2.26 billion in 2025 at a compound annual growth rate (CAGR) of 7.4%. The growth during the historic period can be attributed to increased research and development activities, a rising demand for advanced therapies, higher healthcare expenditures, a growing focus on personalized medicine, and the expanding adoption of digital health technologies.

The post-operative nausea and vomiting market size is expected to see strong growth in the next few years. It will grow to $2.97 billion in 2029 at a compound annual growth rate (CAGR) of 7%. The projected growth during the forecast period can be attributed to the increasing demand for pharmaceuticals, the rise of combination therapy, growing awareness and healthcare investments, a rising geriatric population, and the increasing number of cancer cases.

Key trends expected during this period include advancements in antiemetic therapies, strategic collaborations, innovative drug formulations, the integration of advanced diagnostic tools, and the development of electronic simulation devices.



The increasing number of surgical procedures is expected to drive the growth of the post-operative nausea and vomiting market. Effective management of post-operative nausea and vomiting enhances surgical procedures by improving patient comfort, reducing recovery time, minimizing complications, and ensuring smoother post-operative care, ultimately leading to better surgical outcomes. For example, in November 2024, the Australian Institute of Health and Welfare reported that during the 2023-24 period, 771,600 patients were admitted for surgery from public hospital elective surgery waiting lists, reflecting a 4.9% increase compared to 2022-23. This trend highlights the growing number of surgical procedures, which is fueling the expansion of the post-operative nausea and vomiting market.

Companies in the post-operative nausea and vomiting market are focusing on developing critical injectable medications using advanced emulsion formulations and sustained-release technology to improve treatment efficacy and provide prolonged symptom relief for surgical patients. These critical injectable medications are essential drugs administered via injection to deliver immediate and effective treatment for serious or urgent medical conditions. For example, in July 2024, Avenacy, a US-based specialty pharmaceutical company, introduced Palonosetron Hydrochloride Injection in 0.25 mg/5 mL single-dose vials. This formulation helps healthcare providers reduce dosing errors and improve patient safety. The injection is designed to prevent nausea and vomiting induced by chemotherapy and to manage post-operative nausea and vomiting for up to 24 hours following surgery, offering a reliable treatment option for patients at risk of these conditions.

Major players in the post-operative nausea and vomiting market are Pfizer, Merck, Novartis, GlaxoSmithKline, Takeda Pharmaceutical, Baxter, Teva Pharmaceutical Industries, Sandoz Group, Daiichi Sankyo, Fresenius Kabi, Eisai, Dr. Reddy's Laboratories, Kyowa Hakko Kirin Taiwan, Cipla, Alkem Laboratories, Eagle Pharmaceuticals, Camurus, Helsinn Healthcare, Heron Therapeutics, and Advacare Pharma.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

Report Scope

Markets Covered:

  • Treatment Type: Serotonin Antagonists; Steroids; Dopamine Antagonists; Neurokinin NK-1 Receptor Antagonists; Non-pharmacological Treatment; Other Treatment Types
  • Route of Administration: Oral; Intravenous; Transdermal; Other Route of Administrations
  • Patient Demographics: Pediatric Patients; Adult Patients; Geriatric Patients
  • Surgical Procedure Type: Orthopedic Surgery; Gynecological Surgery; General Surgery; Cardiac Surgery; Ophthalmic Surgery
  • End-User: Hospitals; Ambulatory Surgical Centers; Specialty Clinics; Other End-Users

Sub Segments:

  • Serotonin Antagonists Type: Ondansetron; Granisetron; Palonosetron; Dolasetron; Tropisetron
  • Steroids Type: Dexamethasone; Methylprednisolone; Hydrocortisone; Prednisolone; Betamethasone
  • Dopamine Antagonists Type: Metoclopramide; Droperidol; Prochlorperazine; Domperidone; Chlorpromazine
  • Neurokinin NK-1 Receptor Antagonists Type: Aprepitant; Fosaprepitant; Rolapitant; Netupitant; Casopitant
  • Non-Pharmacological Treatment Type: Acupressure; Aromatherapy; Hypnotherapy; Electroacupuncture; Ginger Supplements
  • Other Treatment Types: Antihistamines; Anticholinergics; Cannabinoids; Combination Therapy; Herbal & Natural Remedies


Key Attributes:

Report AttributeDetails
No. of Pages175
Forecast Period2025 - 2029
Estimated Market Value (USD) in 2025$2.26 Billion
Forecasted Market Value (USD) by 2029$2.97 Billion
Compound Annual Growth Rate7.0%
Regions CoveredGlobal



Post-Operative Nausea and Vomiting Market Competitive Landscape and Company Profiles

  • Post-Operative Nausea and Vomiting Market Competitive Landscape
  • Post-Operative Nausea and Vomiting Market Company Profiles
    • Pfizer Inc. Overview, Products and Services, Strategy and Financial Analysis
    • Merck KGaA Overview, Products and Services, Strategy and Financial Analysis
    • Novartis AG Overview, Products and Services, Strategy and Financial Analysis
    • GlaxoSmithKline Plc Overview, Products and Services, Strategy and Financial Analysis
    • Takeda Pharmaceutical Company Limited. Overview, Products and Services, Strategy and Financial Analysis

Post-Operative Nausea and Vomiting Market Other Major and Innovative Companies

  • Baxter Corporation
  • Teva Pharmaceutical Industries Ltd.
  • Sandoz Group AG
  • Daiichi Sankyo Inc.
  • Fresenius Kabi AG
  • Eisai Co. Ltd.
  • Dr. Reddy's Laboratories
  • Kyowa Hakko Kirin Taiwan Co. Ltd.
  • Cipla Ltd.
  • Alkem Laboratories Ltd.
  • Eagle Pharmaceuticals Inc.
  • Camurus AB
  • Helsinn Healthcare SA
  • Heron Therapeutics Inc.
  • Advacare Pharma

For more information about this report visit https://www.researchandmarkets.com/r/qb9pxb

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Post-Operative Nausea and Vomiting Market

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