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Extracellular ASC has a crucial role in aggregation and deposition of amyloid A fibrils leading to associated chronic inflammatory conditions.
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Plasma levels of inflammasome ASC show promise as a biomarker of early cognitive decline in older adults.
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Inflammation resulting from activation of more than one type inflammasome and ASC specks contribute to development and progression of neurological disease
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PAD, characterized by vascular inflammation and associated calcification, affects 8.5 million people in the United States and contributes to more than 50,000 limb amputations annually, yet there are...
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White paper summarizes the research of leading inflammasome experts, Drs. Helen Bramlett, Juan Pablo de Rivero Vaccari, W. Dalton Dietrich, and Robert W. Keane, University of Miami Miller School of...